Yes, it is possible to cruise from Siem Reap to Saigon. It is difficult to compare how quick it is in term of time with overland journey because it stops for sighseeing visits on the way. But it can be said that a cruise is much more interesting than an overland journey.Try it and you will see.
We will visiting Saigon this year and wonder if it ‘s possible to cruise from Siemreap to Saigon? How quick and convenient is it in comparison with overland journey